“The Devil’s Hands Are Idle Playthings” (Season 4, Episode 18)

Because of how many times Futurama has been canceled or almost canceled, the writers have had a few different chances to craft series finales. The first of these is still one of the best, featuring Fry making a deal with the robot devil so he can play a perfect opera for Leela using a strange and hard-to-play instrument. In the end, Leela and Fry share a sweet moment only when he betrays the Devil and uses his own (unskilled) hands to play a simple song for her. Shit, more dust in my eyes.