Paradox, makers of epics like Crusader Kings and Europa Universalis, have a new grand strategy game coming called Imperator: Rome
https://lastchance.cc/crusader-kings-ii-the-kotaku-re-review-1783955128%3C/a%3E%3C/p%3E
In terms of timing, it’s “set in the tumultuous centuries from Alexander’s Successor Empires in the East to the foundation of the Roman Empire”, so there’s the potential for a lot of alternate history-making.
It’s out in 2019.